The screening marks the first time the 1992 film will play on the big screen in Saudi Arabia since it was shot 30 years ago.
The Red Sea International Film Festival will host a special screening of Malcolm X (1992) which will be attended by the academy award-winning director Spike Lee.
The biopic tells the story of a leading African American and civil rights activist, and one of the most remarkable figures in American 20th-century history.
Denzel Washington stars, portraying three personalities in one body, Malcolm Little, Malcolm X, and El-Hajj Malik El-Shabazz.
Malcolm Little, a young black hoodlum in jazz age Harlem, is incarcerated. In jail, he joins the political movement Nation of Islam, changing his name to Malcolm X.
A great orator in the civil rights movement, X becomes a thorn in the side of the establishment and key member of the nation of Islam. His life changes again on a pilgrimage to Mecca, where he gains a deeper understanding of the central teachings of Islam and discovers a more accommodating outlook, taking on the moniker El-Hajj Malik El-Shabazz.
The film was the first Hollywood feature film to be granted permission to shoot in Mecca on the condition that he hired an all-Muslim film crew.
Following the screening, the Oscar-winning filmmaker will lead a public masterclass, presenting his journey in independent filmmaking, a career that spans over 30 years. This forms part of a series of sessions with international industry leaders attending the film festival.